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Heparan-Sulfate Proteoglycans Influence Alzheimer's Disease Cell Pathology

Researchers utilized mouse astrocytes and human cell cultures to investigate how HSPGs influence autophagy, mitochondrial function, and lipid synthesis.

They also explored whether altering HSPG signaling could mitigate the effects of mutated presenilin (PSEN1) in Drosophila models.

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#Alzheimers #neuroscience #HSPG #Autophagy #Mitochondria #LipidSynthesis #PSEN1 #Drosophila #CellPathology #Astrocytes
5 months ago

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