Creative Biogene is a leading company offering high-quality Staphylococcus aureus gene expression service for our esteemed clients around the world across both academic institutions and biotech/pharmaceutical industries. With our strong technical force, unparalleled customized service and fast delivery time, Creative Biogene specializes in providing more cost-effective gene expression service to accelerate the global research in microbial enzymes.

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Creative Biogene possesses significant expertise and experience in microbial fermentation development and is dedicated to integrate world-wide resources for those who have demands for microbial factory manufacturing.

Fermentation is the process that engineered microorganisms produce large amounts of added-value intermediates or chemicals in a designed bioreactor. These products can be food supplements, pharmaceuticals, industrial platform compounds and others. Fermentation is a part of the upstream process and it occurs before recovery, purification, formulation, filling and packaging in the biomanufacturing workflow.

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Creative Biogene is a leading company offering the best microbial gene expression service. Backed by years of development and research experience, our talented scientists will help you achieve your research goals quickly and efficiently. They would research closely with you to offer your one stop service in microbial gene expression system. All you need to do is simply provide the gene sequences.

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CRISPR/Cas9 PlatformCB dedicates to improve the transformation efficiency of plant and optimize the genome editing system for years. Now, we proudly offer base editing service to introduce single nucleotides change in many species, including rice, tomato, Arabidopsis and tobacco. With years of experience in plant genome editing, our scientists are confident to bring customer high-quality service with the latest technology. Moreover, considering the limitation of editing window scope, we will assist you with free counseling and evaluation for specific project.

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CRISPR activation (CRISPRa) is a CRISPR tool that provides a powerful way to activate genes on a large scale in a focused manner. CRISPRa takes full advantage of a modified version of dCas9, a Cas9 mutation that does not have endonuclease activity, and fused with transcriptional activators. The screening of CRISPR-based transcriptional activation has been used to research mechanisms of human diseases, screen drug targets, and establish causal relationships between gene expression and cell fate determination. In addition, CRISPR-based gene activation is expected to be used to target endogenous gene regulatory elements to increase the expression level of normal gene copies to correct diseases caused by haploid function.

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CRISPR/Cas9 PlatformCB is a professional genetic editing biotechnology company that provides transgenic mouse models for biomedical research and drug discovery. We will provide you with a one-stop-shop from experimental design strategies to successful mouse model generation. The CRISPR/Cas9 platformCB offers CRISPR-based knock-in mice at a very competitive price and complete in 3-4 months. We guarantee delivery of at least 2 founders or 3 F1 animals for knockin.

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Creative Biogene provides a range of premade mRNA products for diverse applications, such as regenerative medicine, vaccination, disease treatment, and cell engineering. Our state-of-the-art facilities and experienced team ensure cost-effective and high-quality solutions tailored to your needs. Contact us for any specific requirements; we look forward to collaborating on your projects.

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Adeno-associated virus (AAV) is a powerful vector system used to transduce cells in vivo. Recombinant AAV can efficiently deliver genetic material to both dividing and non-dividing cells. AAV is replication-defective, nonpathogenic, and noncytotoxic, and can maintain physiologically relevant expression levels in cells and tissues. Currently, AAV has become one of the most promising viral vectors for gene therapy.
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Reporter genes, like GFP or Luciferase, are vital tools in gene expression studies. They are attached to a gene of interest's regulatory sequence for visual identification in cell culture or organisms. Our purified reporter lentiviruses offer single or dual reporter vectors with fluorescent (eGFP, mCherry) and bioluminescent (Firefly, Renilla) markers. These lentiviruses provide a sensitive, dynamic, and straightforward method for promoter activity measurement, gene regulation studies, and drug screening.

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Creative Biogene offers a trusted and efficient virology testing service for biotechnology products and clinic products. Our virologist team is dedicated to developing excellent virology testing services for clients. Based on the experienced staff and state-of-the-art technology, we will provide virology testing services with high quality and convincing results. Following the guideline of Food and Drug Administration, ICH and WHO, Creative Biogene employs multiple and validated assays for virology testing, including in vivo assay, in vitro assay, PCR-based assay and cell-based assay. Meanwhile, custom testing service is welcome.

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