Creative Biogene is developing stable cell lines overexpressing human / mouse/ rat miRNA precursors covered in the current miRbase. Our miRNA overexpression stable cell lines are constructed by lentivirus transduction or non-viral plasmid transfection of vectors optimized by our scientists to enable expression and maturation of miRNAs inside cells. These cell lines are valuable tools for studying miRNA gain-of-functions and identifying the potential target genes.

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Creative Biogene provides world-class MicroRNA (miRNA) sponge service and we have been perfecting MicroRNA sponge service for many years. Our microRNA sponge is a RNA molecule with 5-8 tandem miRNA binding sequences that can sequester miRNAs from their endogenous target mRNAs.

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Creative Biogene delivers an extensive portfolio of recombinant drug target proteins with exceptional batch-to-batch consistency, leveraging advanced expression systems and optimized post-translational modifications. Our comprehensive protein collection, manufactured under global pharmacopeia standards and supported by a traceable supply chain, ensures reliable delivery of premium-grade products that meet diverse requirements across the drug development pipeline, from research to GMP-grade levels.

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The application of viral vectors in gene therapy is rapidly developing and the therapeutic results are highly promising. However, actively and passively integrating (viral) vectors may fail to deliver, or trigger severe side effects by undirected or unintended integration into the genome of the target cell. Thus, the analysis of vector integration sites in target cells is extremely important to address both biological and safety issues. Creative Biogene, as one of the leading biotechnology companies, has extensive expertise and experience which are available to provide you with customer LAM PCR service to analyze the viral vector insertion/integration site.

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Creative Biogene offers a comprehensive range of histone modifications assay services for the quantification of methylation, acetylation, phosphorylation, ubiquitination and SUMOylation of histones at all sites. The most comprehensive selection of histone modification research services covers every step of your experimental workflow, from upstream to downstream.

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Herpes simplex virus (HSV) is an enveloped, large linear and double-stranded DNA (~150 kb) virus in the family Herpesviridae. There are two HSV species: Herpes Simplex Virus Type I (HSV-1) and Herpes Simplex Virus Type II (HSV-2), both of which can infect humans and cause diseases. HSV genome replicates by means of a rolling circle mechanism which forms head-to-tail concatamers. In the large genome of HSV, about half of the sequences are non-essential genes, which means they can be replaced with one or multiple transgenes.

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Creative Biogene is a leading company offering high-quality Staphylococcus aureus gene expression service for our esteemed clients around the world across both academic institutions and biotech/pharmaceutical industries. With our strong technical force, unparalleled customized service and fast delivery time, Creative Biogene specializes in providing more cost-effective gene expression service to accelerate the global research in microbial enzymes.

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Creative Biogene possesses significant expertise and experience in microbial fermentation development and is dedicated to integrate world-wide resources for those who have demands for microbial factory manufacturing.

Fermentation is the process that engineered microorganisms produce large amounts of added-value intermediates or chemicals in a designed bioreactor. These products can be food supplements, pharmaceuticals, industrial platform compounds and others. Fermentation is a part of the upstream process and it occurs before recovery, purification, formulation, filling and packaging in the biomanufacturing workflow.

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Creative Biogene is a leading company offering the best microbial gene expression service. Backed by years of development and research experience, our talented scientists will help you achieve your research goals quickly and efficiently. They would research closely with you to offer your one stop service in microbial gene expression system. All you need to do is simply provide the gene sequences.

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CRISPR/Cas9 PlatformCB dedicates to improve the transformation efficiency of plant and optimize the genome editing system for years. Now, we proudly offer base editing service to introduce single nucleotides change in many species, including rice, tomato, Arabidopsis and tobacco. With years of experience in plant genome editing, our scientists are confident to bring customer high-quality service with the latest technology. Moreover, considering the limitation of editing window scope, we will assist you with free counseling and evaluation for specific project.

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