Understanding Glucuronolactone and its Role in the Body

Glucuronolactone, also known as gulonic acid gamma-lactone, is a naturally occurring glucuronide compound that is present in the body. It is a key intermediate in glucose metabolism that is formed through the process of glucuronidation in the liver. Glucuronolactone exists in two enantiomeric forms - D-glucuronolactone and L-glucuronolactone.

D-glucuronolactone is biosynthesized in the liver from glucose through the glucuronidation reaction catalyzed by the enzyme UDP-glucuronosyltransferase. It is formed as an intermediate product during the conversion of glucose to glycogen for storage.

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