Glucuronolactone, also known as glucuronate lactone or β-D-glucuronolactone, is a naturally occurring monosaccharide and a lactone with the chemical formula C6H10O6. It is produced through glucuronic acid metabolism in the liver and plays an important role in various metabolic processes in the body.
In the glucuronolactone is an endogenously produced metabolite with significant physiological roles central to energy production, antioxidant defense, drug metabolism, brain health, connective tissue formation and various other metabolic processes.
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What is Glucuronolactone?Glucuronolactone is a naturally occurring sugar and organic acid found in the body. It is part of the glucuronidation pathway that processes toxins and drugs for removal from the body. Glucuronolactone makes up 0.1% to 0.8% of the dry weight of most animal tissues and...
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Glucuronolactone, also known as gulonic acid gamma-lactone, is a naturally occurring glucuronide compound that is present in the body. It is a key intermediate in glucose metabolism that is formed through the process of glucuronidation in the liver. Glucuronolactone exists in two enantiomeric forms - D-glucuronolactone and L-glucuronolactone.
D-glucuronolactone is biosynthesized in the liver from glucose through the glucuronidation reaction catalyzed by the enzyme UDP-glucuronosyltransferase. It is formed as an intermediate product during the conversion of glucose to glycogen for storage.
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Research in vitro and in animal models suggests glucuronolactone exhibits liver-protecting and regenerative properties.
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