Mouse Retinal Pigment Epithelial Cells are isolated from mouse tissues. Mouse Retinal Pigment Epithelial Cells are cryopreserved at P0 and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume. Mouse Retinal Pigment Epithelial Cells are negative for mycoplasma, bacteria, yeast, and fungi. Mouse Retinal Pigment Epithelial Cells are guaranteed to further expand for 5 population doublings under the conditions provided by Creative Bioarray.

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HSF from Creative Bioarray are isolated from human spleen tissue. HSF are cryopreserved at primary culture and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume. HSF are characterized by their spindle morphology and immunofluorescent method with antibody to fibronectin. HSF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HSF are guaranteed to further expand for 15 population doublings at the condition provided byCreative Bioarray.

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Canine Small Intestinal Epithelial Cells from Creative Bioarray are isolated from small intestinal tissue of pathogen-free laboratory Canine. Canine Small Intestinal Epithelial Cells are grown in a T25 tissue culture flask pre-coated with gelatin-based coating solution for 2 min and incubated in Creative Bioarray’s Culture Complete Growth Medium for 3-5 days.

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Creative Bioarray provides comprehensive and detailed services for stem cell bank characterization to help our customers worldwide in the field of cell banks. We employ multiple assays to assess cell banks from different aspects, including but not limited to PCR, qPCR, next-generation sequencing, and transmission electron microscopy. Rapid and accurate results will be delivered to assist customers in accessing the quality of cell banks as soon as possible.

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Major mammalian cell lines used in the biopharmaceutical industry as host cells for the production of biologics include Chinese hamster ovary (CHO) cells and mouse myeloma cells, including NS0 and Sp2/0 cells. Creative Bioarray provides comprehensive and detailed services for mammalian cell bank characterization to help our customers worldwide in the field of cell banks. We delivered rapid and accurate results to assist customers in accessing the quality of cell banks. Reliable, rapid, and accurate results will be delivered to assist customers in assessing the quality of cell banks.

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As an established leader in the field of cell science, Creative Bioarray's expertise in cell banking is unparalleled. Our QC testing plans meet requirements for cell bank release and are designed to meet regulations with assays validated to GMP standards. Ready-to-use testing schemes may be added to existing strategies or customized for the needs of specific programs.

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Our services not only include hERG inhibition testing but also cover inhibitory assessments of potassium, calcium, and sodium channels, as well as other related channels or receptors. Additionally, we provide "Comprehensive Cardiotoxicity Assessment (CiPA)" and "Langendorff Isolated Perfused Heart Assay" services. These comprehensive and precise assessment methods enable the evaluation of your drug's in vitro cardiotoxicity potential, thereby reducing the risk of development failure due to cardiac safety issues, and consequently minimizing economic losses.

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Hepatocytes in 3D culture are the proper culture models for testing the liver-specific functions in vitro. The functional parameters such as CYP activity, ATP, albumin production, and enzyme content, etc., will be measured based on the customers’ choices. Albumin and urea are synthesized by the liver. As so, they are markers for the ability of the liver to synthesize proteins. CYPs are involved in the metabolism of drugs, chemicals and endogenous substrates. CYP-mediated activation of drugs to toxic metabolites induces hepatotoxicity. Thus, a wide range of assays for liver in vitro models will evaluate your compounds by characterization hepatic functions and their drug-mediated responses.

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IHC, by exploiting the principle of antibodies binding specifically to antigens in biological tissues, is a routine method to detect antigens in cells of a tissue section. It is widely used in the diagnosis of diseases including cancer, neurological disease, digestive disease, etc. Specific molecular markers have been found and verified to be characteristic of particular cellular events in disease such as proliferation, apoptosis and inflammation. Thus it could be used in detection of such changes involved in disease. IHC is also a common method in basic research of disease to help understanding the distribution and localization of biomarkers and differentially expression of proteins in different parts of tissue. Creative Bioarray offers a comprehensive IHC service from project design, marker selection to image completion and data analysis. We are dedicated to satisfied every customer and assist them to achieve their specific research goals.

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The animal models of human diseases are animal experimental objects and materials established in biomedical scientific research with the mimicry of human diseases. The use of animal models is an important experimental method and means in modern biomedical research, which helps to more conveniently and effectively understand the occurrence, development, and prevention measures of human diseases.

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