Colorectal cancer (CRC) remains one of the leading causes of cancer-related deaths worldwide. As research into the molecular mechanisms of this disease deepens, the demand for reliable, genetically representative in vitro models grows. Among these, the SW480 cell line has earned recognition as one of the most widely used human colon cancer models. First established from a 50-year-old male patient with primary adenocarcinoma of the rectum, SW480 cells provide researchers with a versatile platform for exploring tumor biology, drug response, and gene function.
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