Hepatocytes in 3D culture are the proper culture models for testing the liver-specific functions in vitro. The functional parameters such as CYP activity, ATP, albumin production, and enzyme content, etc., will be measured based on the customers’ choices. Albumin and urea are synthesized by the liver. As so, they are markers for the ability of the liver to synthesize proteins. CYPs are involved in the metabolism of drugs, chemicals and endogenous substrates. CYP-mediated activation of drugs to toxic metabolites induces hepatotoxicity. Thus, a wide range of assays for liver in vitro models will evaluate your compounds by characterization hepatic functions and their drug-mediated responses.

https://www.creative-bioar...