Stem Cell Manufacturing: Exploring the Technological Advancements Revolutionizing Medical Care

Stem Cell Manufacturing like CRISPR-Cas9 have enabled precisely modifying stem cell genomes. Researchers can knock-out or overexpress specific genes to understand their roles and direct cell fate. This helps generate stem cell lines with tailored properties according to application. For example, scientists have used CRISPR to disrupt HLA gene in stem cells to avoid immune rejection after transplant. Gene editing also allows creating “designer” stem cell lines carrying therapeutic genes which upon differentiation secrete factors to treat diseases.
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