Intranasal Drug Delivery Devices: The Next Generation of Medication Administration
The nasal cavity presents a promising non-invasive route for administering various drugs and delivering medications into systemic circulation. Some key benefits of the intranasal route include rapid drug absorption, avoidance of first-pass metabolism, easy administration, and direct delivery of drug payloads to the brain through olfactory or trigeminal neural pathways. This has sparked significant interest in developing advanced intranasal drug delivery devices for a diverse range of therapeutic applications.
Anatomy and Physiology of the Nose
The nasal cavity has a surface area of about 150 cm2 lined with highly vascularized mucosa only about 0.1 mm thick, which facilitates rapid absorption of drugs administered Intranasal Drug Delivery Devices. The thin epithelial barrier and rich blood supply enable direct drug entry into systemic circulation bypassing hepatic first-pass metabolism. The nose also provides direct nose-to-brain pathways for l
The nasal cavity presents a promising non-invasive route for administering various drugs and delivering medications into systemic circulation. Some key benefits of the intranasal route include rapid drug absorption, avoidance of first-pass metabolism, easy administration, and direct delivery of drug payloads to the brain through olfactory or trigeminal neural pathways. This has sparked significant interest in developing advanced intranasal drug delivery devices for a diverse range of therapeutic applications.
Anatomy and Physiology of the Nose
The nasal cavity has a surface area of about 150 cm2 lined with highly vascularized mucosa only about 0.1 mm thick, which facilitates rapid absorption of drugs administered Intranasal Drug Delivery Devices. The thin epithelial barrier and rich blood supply enable direct drug entry into systemic circulation bypassing hepatic first-pass metabolism. The nose also provides direct nose-to-brain pathways for l
2 months ago
