Latest Advancements in Neurodegenerative Disease Treatment

Stem Cell Therapy

Stem cell therapy is a promising new treatment approach for several neurodegenerative diseases. Stem cells have the potential to differentiate into neurons and other cell types in the brain and central nervous system. By implanting stem cells in areas affected by neurodegeneration, it may be possible to replace dying cells and stop or slow down the progression of these diseases. Several clinical trials are currently investigating the safety and efficacy of stem cell therapy for conditions like Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis (ALS), and Huntington's disease.

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Concussion History in Rugby Players Linked to Neurodegenerative Disease Biomarkers

Durham University reveals higher levels of biomarkers linked to neurodegenerative disease in retired rugby players with multiple concussions, underscoring the need for early diagnosis and improved safety measures.

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RNA binding proteins (RBPs) are linked to the prevalent hereditary disorder known as fragile X syndrome (FXS). It was discovered that FMRP, or fragile X mental retardation protein, was absent in cases of FXS. A significant and actively researched selective RBP is FMRP. It is present in the soma, dendrites, and axon of the neuron and is crucial for healthy synaptic function. Between 85 and 90 percent of FMRPs are engaged in the functions of polysomes, including as translational control and neurodegeneration.

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This gene produces a protein that controls autophagy, a starvation-induced catabolic process of destruction. The encoded protein functions as a part of the vesicle-trafficking processes-mediating phosphatidylinositol-3-kinase (PI3K) complex. This protein is believed to be involved in a number of cellular processes, such as apoptosis, neurodegeneration, and cancer. There are various transcript variations produced by alternative splicing.
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