Cancer Monoclonal Antibodies: Targeting Tumors Precisely for Improved Treatment Outcomes

Monoclonal antibodies (mAbs) are engineered antibodies that are derived from a single clone and bind to a specific antigen on cells. Since the 1970s, researchers have worked to harness the power of antibodies in targeting and treating diseases like cancer. The first breakthrough came in 1975 when scientists devised a technique for fusing myeloma cells with spleen cells from immunized mice to generate hybridomas that could produce monoclonal antibodies indefinitely. This "hybridoma technology" paved the way for mass production of engineered antibodies that reacted with a single antigen.

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