Superoxide dismutase (SOD) catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a critical role in the defense of cells against the toxic effects of oxygen radicals. SOD competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby SOD promotes the activity of NO. SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines, and transgenic mice by preventing the conversion of NO to peroxynitrate, an inducer of apoptosis. https://diagnostic-enzymes...

Xanthine oxidase is a form of xanthine oxidoreductase, a type of enzyme that generates reactive oxygen species. These enzymes catalyze the oxidation of hypoxanthine to xanthine and can further catalyze the oxidation of xanthine to uric acid. These enzymes play an important role in the catabolism of purines in some species, including humans. https://diagnostic-enzymes...

In enzymology, a quinoprotein glucose dehydrogenase (EC 1.1.5.2) is an enzyme that catalyzes the chemical reaction: D-glucose + ubiquinone ↔D-glucono-1,5-lactone + ubiquinol. Thus, the two substrates of this enzyme are D-glucose and ubiquinone, whereas its two products are D-glucono-1,5-lactone and ubiquinol. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with a quinone or similar compound as acceptor. This enzyme participates in pentose phosphate pathway. It employs one cofactor, PQQ. https://diagnostic-enzymes...

Probiotics are living microorganisms that co-exist with the human. Different from pathogenic microorganisms, probiotics are beneficial, sometimes essential to health. For example, the intake of probiotics can increase the number of beneficial bacteria in the intestine, maintain the dynamic balance of intestinal flora, and enhance gastrointestinal health. Creative Enzymes has established a specialized production site for freeze-dried probiotics and provides custom probiotic formulation. Our probiotics products include Lactobacillus, Saccharomyces, Bifidobacterium, Lactococcus, Streptococcus, Leuconostoc, Bacillus, etc., covering food science, nutrition, microbiology, bioengineering, fermentation engineering, and other fields. https://probiotic.creative...

Leuconostoc mesenteroides is a species of lactic acid bacteria associated with fermentation, under conditions of salinity and low temperatures (such as lactic acid production in fermented sausages). In some cases of vegetable and food storage, it was associated with pathogenicity (soft rot, slime and unpleasant odor). L. mesenteroides is approximately 0.5-0.7 µm in diameter and has a length of 0.7-1.2 µm, producing small grayish colonies that are typically less than 1.0 mm in diameter. It is facultatively anaerobic, Gram-positive, non-motile, non-sporogenous, and spherical. It often forms lenticular coccoid cells in pairs and chains, however, it can occasionally forms short rods with rounded ends in long chains, as its shape can differ depending on what media the species is grown on. https://probiotic.creative...

Bacilli are gaining interest in human-health related functional food research coupled with their enhanced tolerance and survivability under a hostile environment of the gastrointestinal tract. Besides, Bacilli are more stable during processing and storage of food and pharmaceutical preparations, making them a more suitable candidate for health-promoting formulations. Further, Bacillus strains also possess biotherapeutic potential, which is connected with their ability to interact with the internal milieu of the host by producing a variety of antimicrobial peptides and small extracellular effector molecules. https://probiotic.creative...

Our high-quality, organic, adaptogenic, finely filtered mushroom extracts can be used as nutritional supplement, in cosmetics and skin care and in agriculture. Creative Enzymes provide 20 mushroom extracts in liquid or powder form, including Tremella Fuciformis extract, Sparassis crispa extract, Schizophyllan, Cordyceps extract etc. https://www.creative-enzym...

A thermostable Alpha-L-Rhamnosidase (Naringinase, RhamA) that catalyzes the cleavage of the bond between terminal L (+)-rhamnose and the aglycone of rhamnose-containing glycosides. The enzyme is very active on naringin but has also substantial activity with hesperidin as substrate. https://www.creative-enzym...

Alcohol dehydrogenases (ADH) are a group of dehydrogenase enzymes that occur in many organisms and facilitate the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+ to NADH). In Humans and many other animals, they serve to break down alcohols that otherwise are toxic, and they also participate in geneRation of useful aldehyde, ketone, or alcohol groups during biosynthesis of various metabolites. In yeast, plants, and many bacteria, some alcohol dehydrogenases catalyze the opposite reaction as part of fermentation to ensure a constant supply of NAD+. https://www.creative-enzym...

Mutation Detection Kit provides a simple, reliable, and rapid method for the detection of site specific cleavage of genomic DNA that is extracted from cells transfected with constructs expressing engineered nucleases such as Transcription activator-like effector nucleases (TALEN), Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9, or Zinc-finger nucleases (ZFN). Mutation Detection Kit includes High-Fidelity DNA polymerase for amplifying the target regions from cells, and T7 Endonuclease I for recognizing and detecting the mismatches caused by gene editing tools. It provides an easy and reliable approach for estimating the efficiency of genome editing. https://molecular-tools.cr...

NLS-Cas9-EGFP is a fusion protein contains a nuclear localization sequence (NLS) on its N terminal and EGFP on the C terminal. The EGFP can be used as a reporter for tracking or sorting transfected cells, which enables the possibility of enriching cell populations for desired genome edits via fluorescence activated cell sorting (FACS). It significantly reduces the labor and cost associated with single cell cloning and genotyping in genome editing applications. https://molecular-tools.cr...

Cas9-C-NLS nuclease is the recombinant Streptococcus pyogenes Cas9 (wt) protein with a C-terminal nucleic localization signal (NLS). It can be used for genome editing by inducing site-specific DNA double stranded breaks. Cas9 protein forms a very stable ribonucleoprotein (RNP) complex with the guide RNA (gRNA) component of the CRISPR/Cas9 system, which can localize to the nucleus immediately once entering the cell with the guide of the NLS. https://molecular-tools.cr...

In enzymology, a glucose 1-dehydrogenase (EC 1.1.1.47) is an enzyme that catalyzes the chemical reaction:beta-D-glucose + NAD (P)+↔ D-glucono-1,5-lactone + NAD (P)H + H+. The 3 substrates of this enzyme are beta-D-glucose, NAD+, and NADP+, whereas its 4 products are D-glucono-1,5-lactone, NADH, NADPH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. https://diagnostic-enzymes...

Malate dehydrogenase is an enzyme in the citric acid cycle that catalyzes the conversion of malate into oxaloacetate (using NAD+) and vice versa (this is a reversible reaction). Malate dehydrogenase is not to be confused with malic enzyme, which catalyzes the conversion of malate to pyruvate producing NADPH. Malate dehydrogenase is also involved in gluconeogenesis, the synthesis of glucose from smaller molecules. Pyruvate in the mitochondria is acted upon by pyruvate carboxylase to form oxaloacetate, a citric acid cycle intermediate. https://diagnostic-enzymes...

Lactobacillus salivarius is a probiotic bacteria species that has been found to live in the gastrointestinal tract and exert a range of therapeutic properties including suppression of pathogenic bacteria. https://probiotic.creative...