Advances in Hemostasis Diagnostics: Evaluating Bleeding and Thrombosis

Hemostasis is the physiological process that controls bleeding at the site of vessel injury through blood coagulation and clot formation. When the vascular endothelial lining is disrupted, platelets attach to exposed collagen at the site of injury, triggering coagulation reactions that lead to fibrin deposition and clot formation. Hemostatic balance relies on a complex interplay between procoagulant and anticoagulant factors circulating in plasma and those present on cell surfaces. Evaluation of hemostasis through laboratory diagnostics provides critical information to determine bleeding disorders and risks of thrombosis.

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