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Cephalosporin Drugs: An Overview of These Broad Spectrum Drugs

History of Cephalosporins
Cephalosporins were first discovered in 1948 from a fungus named Cephalosporium. The first generation cephalosporin antibiotic cephalexin was launched in the market in 1964. Since then, several generations of cephalosporins have been developed with improved spectrum and effectiveness.

The first generation cephalosporins included cephalexin, cefadroxil and cephalothin. They were mainly effective against gram-positive bacteria like Staphylococcus. They had limited activity against gram-negative bacteria. Due to their narrow spectrum, first generation cephalosporins are not commonly used now.

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09:46 AM - Feb 24, 2025 (UTC)

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