There is always a discussion regarding Is E-Express an Airline? Or not, Instead of being an airline, E-Express is an online travel agency. It allows customers to look for and reserve flight, hotel, and vacation packages. Despite not running flights, E-Express partners with many airlines to provide passengers with choices. This implies that although E-Express can help you compare costs and identify the best offers for your trip, the airlines they work with are in charge of actually running the flights.