Immuno-oncology Drugs: A New Frontier in Cancer Treatment

Immuno-oncology is an emerging field that utilizes the body's own immune system to fight cancer. Traditional cancer treatments like chemotherapy, radiation therapy, and surgery aim to directly kill cancer cells.

Checkpoint inhibitors are one of the most common classes of Immuno-oncology Drugs. These drugs target inhibitory checkpoint molecules on T cells that normally help prevent autoimmune disease. However, some tumors exploit these checkpoints to evade immune detection.

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DNA Repair Drugs: A Promising New Class of Cancer Treatments

All cells experience DNA damage on a regular basis from various environmental and endogenous sources such as radiation, chemicals, and reactive oxygen species produced during normal cellular metabolism. Under normal circumstances, cells have robust DNA repair mechanisms that detect and fix alterations to the DNA structure before they can lead to mutations.

One of the most clinically advanced classes of DNA Repair Drugs are PARP (Poly ADP-Ribose Polymerase) inhibitors. PARP enzymes play an important role in repairing single-strand DNA breaks through the base excision repair pathway.

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