Regulatory-compliant residual host cell DNA quantification for biopharmaceutical products using qPCR and highly sensitive fluorescence-based assays. Our validated methods detect trace amounts of contaminating DNA with sensitivity down to picogram levels, meeting FDA, EMA, and ICH guidelines. Critical for ensuring the safety of biologics, vaccines, cell therapy products, and recombinant proteins. Creative Proteomics provides complete documentation for regulatory submissions with rapid turnaround times to support your manufacturing and quality control processes. https://www.creative-prote...

Precise antibody sequencing without reference genome requirements using our proprietary multi-enzymatic digestion and advanced MS/MS fragmentation techniques. We determine complete heavy and light chain amino acid sequences with coverage of CDRs and framework regions. Essential for therapeutic antibody development, hybridoma cell line authentication, biosimilar characterization, and intellectual property protection. Creative Proteomics provides comprehensive sequence reports with confidence scores and post-translational modification mapping to support your antibody engineering efforts. https://www.creative-prote...

Discover unknown metabolites and comprehensive pathway changes with our state-of-the-art untargeted metabolomics platform. Using high-resolution LC-MS/MS with advanced data processing algorithms, we detect thousands of metabolites in a single analysis without predetermined targets. Perfect for biomarker discovery, drug metabolism studies, nutritional research, and environmental metabolomics. Creative Proteomics delivers sophisticated statistical analysis, pathway mapping, and biological interpretation to transform complex metabolic data into actionable insights for your research. https://www.creative-prote...

High-resolution N-glycan characterization service combining enzymatic release, fluorescent labeling, and multi-dimensional chromatography with mass spectrometry detection. Our comprehensive approach identifies glycan structures, quantifies relative abundance, and characterizes site-specific glycosylation patterns. Essential for biopharmaceutical quality control, glycoprotein research, biomarker discovery, and immunological studies. Creative Proteomics offers customized workflows for various sample types with detailed reports including glycan structure assignment and statistical analysis of glycosylation changes. https://www.creative-prote...

Industry-leading GST pull-down services to verify and characterize protein-protein interactions with exceptional specificity and sensitivity. Our optimized protocols minimize background and maximize true interaction detection. Results include comprehensive binding partner identification using mass spectrometry, interaction strength assessment, and competition analysis options. Ideal for validating yeast two-hybrid results, mapping protein domains involved in interactions, and discovering novel binding partners. Creative Proteomics delivers clear, publication-ready data with expert consultation. https://www.creative-prote...

Detailed glycolysis metabolic pathway assessment using highly sensitive analytical methods to quantify all key glycolytic intermediates from glucose to pyruvate. Our comprehensive analysis reveals flux changes, bottlenecks, and pathway regulation in various physiological and pathological conditions. Essential for cancer metabolism research, diabetes studies, bioproduction optimization, and sports physiology. Creative Proteomics provides integrated data interpretation with pathway visualization to help you understand energy metabolism alterations in your experimental models. https://www.creative-prote...

Reveal complex protein-protein interactions and structural relationships with our sophisticated crosslinking analysis platform. Combining chemical crosslinking with high-resolution mass spectrometry, we identify direct binding partners, characterize protein complexes, and map interaction interfaces with amino acid-level precision. Valuable for structural biology, drug development, and understanding cellular signaling networks. Creative Proteomics offers customized crosslinking strategies, advanced data analysis, and visualization tools to transform your protein interaction research. https://www.creative-prote...

Comprehensive tricarboxylic acid cycle metabolite quantification using state-of-the-art LC-MS/MS technology. Our service provides detailed profiling of citrate, isocitrate, α-ketoglutarate, succinate, fumarate, malate, and other key TCA intermediates. Essential for understanding cellular energy metabolism, mitochondrial dysfunction, cancer research, and metabolic disorders. Creative Proteomics delivers precise, reproducible results with expert interpretation to help identify metabolic bottlenecks and pathway dysregulation in your biological systems. https://www.creative-prote...

Expert peptide and protein sequencing utilizing cutting-edge mass spectrometry technology for precise amino acid sequence determination. Our advanced analytical platform delivers superior resolution and sensitivity for complex samples. Ideal for protein characterization, post-translational modification analysis, biomarker discovery, and pharmaceutical development. Creative Proteomics provides customized solutions with rapid turnaround times and comprehensive data interpretation to accelerate your research and development projects. https://www.creative-prote...

Creative Proteomics provides a specialized rabbit cytokine multiplex assay that allows for the simultaneous measurement of multiple cytokines in rabbit samples. Our cutting-edge technology ensures accurate quantification, enabling researchers to explore immune responses, inflammatory processes, and disease mechanisms in rabbits. With a focus on precision and reliability, we offer customized solutions to meet your specific research needs. Rely on us for high-quality data that advances your understanding of cytokine dynamics in rabbit models for veterinary and biomedical research. https://cytokine.creative-...