Creative Biolabs can provide stem cell-based therapeutics development. Since stem cells are vital to the development, growth, maintenance, and repair of brains, bones, muscles, nerves, blood, skin, and other organs, we provided disease-specific stem cell therapy services, iPSC-derived cell therapy services. Also, to fit the rapid growth of stem cell therapy around the world, our scientists are using stem cells to develop customized disease modeling and to facilitated new drugs discovery for clients worldwide. https://www.creative-biola...

Stem cell therapy and research are revolutionizing medicine, offering new hope for treating diseases like Parkinson’s and diabetes. By harnessing the regenerative potential of stem cells, researchers aim to develop innovative treatments that can repair damaged tissues and improve patient outcomes. https://www.creative-biola...

Stem cell research and therapy impact factor is crucial for evaluating scientific progress in regenerative medicine. High impact factors indicate influential studies that contribute to advancements in treatment options, promoting understanding of stem cell applications in various medical fields. https://www.creative-biola...

At Creative Biolabs, we enhance your research and data relevancy by acquiring and reprogramming induced pluripotent stem cells (iPSC) from a specific patient's clinical profile. Our pipeline is designed to meet the clients' projects and specific assay requirements for cellular characteristics and functions. Learn more about iPSC-derived cell therapy development. https://www.creative-biola...

Creative Biolabs has developed assay services for gene & cell therapy products. We have the expertise and directly relevant experience to develop, validate, and perform your cell therapy-related assays. With our business operating expertise, we are guaranteed to develop proprietary assays, including genetic/epigenetic analysis, using both in vivo assay development and in vitro assay development models, to better predict human outcomes. https://www.creative-biola...

stem cell research & therapy

We have extensive expertise in all aspects of cell therapy research and our extensive range of assays and services support cell therapy development. We offer both routine and custom-designed assays that are regulatory compliant to ensure the safety, purity, and efficacy of your drug product. In addition, we are committed to providing high-quality, GMP-compliant testing at all steps of your drug development program. https://www.creative-biola...

How to test complement activation?

Over the past two decades, highly specific monoclonal antibodies have been generated that recognize only neoepitopes exposed in the activation product, which enables direct capture of complement activation products by ELISA or high-capacity immunosorbents without the interference of the nonactivated component. A number of complement activation products have been tested by this method, including the classical pathway (C1rs-C1 inhibitors, C4d and C4bc), alternative pathways (Ba, Bb, and C3bBЬP), C3 (C3a, iC3b/C3bc, and C3d) and terminal reactions sequence (C5a and sC5b-9).

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The total complement activity contributes to a comprehensive understanding of the activation status of the complement system to better define disease occurrence, severity, and response to treatment. Therefore, the total complement activity test has very important clinical value in the diagnosis and subsequent treatment of complement-related diseases. The most common methods of total complement activity tests include hemolysis assays, liposome lysis, and enzyme-linked immunosorbent assays (ELISAs). https://www.creative-biola...

Why Do complement activation test?

complement activation tests are developed to find patients suffering from complement deficiency. Deficiencies in complement components and their regulatory molecules have been reported in a variety of diseases, such as recurrent infections, autoimmune and renal diseases. Today, these tests are also widely used for drug development of new complement-targeted drugs. Therefore, functional or activity tests are of great importance to screen complement defects and complement-targeted drug development. https://www.creative-biola...

Creative Biolabs provides a range of ready-to-use aptamers targeting proteins, compounds, bacteria, viruses and cells. You can find ones of interest and the products with high purity and strict QC will be delivered for you. Learn more about aptamer assay protein. https://www.creative-biola...

Creative Biolabs provides a range of ready-to-use aptamers targeting proteins, compounds, bacteria, viruses and cells. You can find ones of interest and the products with high purity and strict QC will be delivered for you. Learn more, https://www.creative-biola...

The Classic Way in Aptamer The conventional method for aptamer screening, known as systematic evolution of ligands by exponential enrichment (SELEX), rapidly identifies optimal binding sequences from a random population. SELEX involves multiple rounds of selection and amplification cycles. Learn more, https://www.creative-biola...

The PINK1 gene (encoding the PINK1 protein) is a known pathogenic variant gene that causes PD. A large number of in vitro and biochemical experiments have shown that PINK1 protects neuronal cells by inducing autophagy of damaged mitochondria, and loss of PINK1 function leads to neuronal cell death in PD. Learn more, https://neuros.creative-bi...

Mutations in LRRK2 are risk factors for and causes of sporadic and familial Parkinson's disease (PD). LRRK2 is one of the major drug targets for PD. Researchers will be able to observe how this protein works inside cells and more quickly determine how potential drugs affect its function. This will accelerate drug discovery and provide new hope for people with this debilitating disease. Learn more, https://neuros.creative-bi...

The primary component of amyloid plaques identified in the brains of Alzheimer's disease (AD) patients is amyloid beta, often known as Aβ or Abeta, which is a group of protein peptides produced when β- and γ-secretases cleave the amyloid precursor protein (APP). Amyloid plaques are formed by the spontaneous assembly of monomeric Aβ into soluble Aβ oligomers, that aggregate to form insoluble fibrils. Learn more, https://neuros.creative-bi...